Recombinant CD4 (Clenoliximab Biosimilar) 抗体
Quick Overview for Recombinant CD4 (Clenoliximab Biosimilar) 抗体 (ABIN7795103)
抗原
抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
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Expression System
- Mammalian cells
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原理
- Clenoliximab Biosimilar, CD4 Monoclonal Antibody
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产品特性
- Clenoliximab Biosimilar uses the same protein sequences as the therapeutic antibody clenoliximab. Clenoliximab is a chimeric monoclonal antibody from Macaca irus against CD4 which acts as an immunomodulator. It has investigated for the treatment of rheumatoid arthritis. Clenoliximab is a macaque-human chimeric monoclonal antibody (immunoglobulin G4)that binds specifically to the CD4 receptor present on T-lympocytes (Helper T lymphocytes). CD-4 lymphocytes are implicated in the pathogenesis of rheumatoid arthritis (RA). Clenoliximab coats the CD4 T-lymphocytes and thus down-modulates the CD4 T-lympocytes in a dose and concentration-dependent manner without decreasing the amount of CD4 T-lympocytes in circulation.
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纯化方法
- Protein A or G affinity column
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纯度
- >95 % by reducing SDS-PAGE
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内毒素水平
- < 1 EU per 1 mg of the protein by the LAL method
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免疫原
- Human CD4
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anti-CD4 (Clenoliximab Biosimilar) antibody
适用: 人, Chimpanzee FACS, BR, ELISA, IHC, SPR 宿主: Human Monoclonal CE9-1 unconjugated Recombinant Antibody
anti-CD4 (Clenoliximab Biosimilar) antibody适用: 人, Chimpanzee FACS, BR, ELISA, IHC, SPR 宿主: 兔 Chimeric CE9-1 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- > 3 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CD4 (Clenoliximab Biosimilar)
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别名
- Clenoliximab Biosimilar
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物质类
- Biosimilar
抗原
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